Monday, February 26, 2007

NEWRON vol I issue III (2-23-07)

Edited by: Natan Davidovics



http://www.washingtonpost.com/wp-dyn/content/article/2007/02/01/AR2007020101623.html

New Technique Allows 'Feeling' in Artificial Arm

By Steven Reinberg
HealthDay Reporter
Thursday, February 1, 2007; 12:00 AM

An innovative method of nerve regrowth now allows a patient with a prosthetic arm to feel its movements.





http://www.newscientisttech.com/article/dn11179-haptic-glove-to-touch-on-vi%20%20rtual-fabrics.html

Haptic glove to touch on virtual fabrics

  • 18:28 13 February 2007
  • NewScientist.com news service
  • Tom Simonite
"Virtual fabric" that feels just like the real thing is being developed by a group of European researchers. Detailed models of the way fabrics behave are combined with new touch stimulating hardware to realistically simulate a texture's physical properties.



(No link for the next one, article attached below)

We'll all be cyborgs someday, scientist says

British professor foresees day when most people will be implanted with computer chips.

By Don Melvin
INTERNATIONAL STAFF
Saturday, December 23, 2006
READING, England — In "Casino Royale," the latest James Bond movie, Bond is implanted with a microchip that allows headquarters to track his whereabouts and monitor his vital signs.
If a British cybernetics expert is right, the day will come when most people are implanted with chips — and the real-life chips will do a lot more than Bond's does.
Rodica Socolov photos
FOR COX NEWSPAPERS
British professor Kevin Warwick was able to make a robotic hand move using signals transmitted from his brain through a chip implanted by doctors in 2002. He had a less sophisticated implant in 1998.
Robot Morgui can combine input from several sensory receptors to understand its environment.
Kevin Warwick, a professor of cybernetics at the University of Reading, has firsthand knowledge. In 1998, he had a chip surgically inserted into his left arm, becoming, he thinks, the first human ever implanted with a computer chip.
Since then, he's had a more sophisticated chip connected directly to his nervous system. He is still working toward his grandest experiment: having a chip implanted in his brain.
"I want to become a cyborg," he said with an infectious grin. "I can see the advantages."
A cyborg is a mixture of man and machine. And cybernetics is the study of communication and control between humans and computers.
Warwick, 52, presides excitedly over the apparent chaos at the university's MAD lab. (The name stands not for madness but for Mobile Autonomous Devices.)
Cables and machine parts litter workbenches. On the floor, two robots the size of model cars race around, mapping their environment and learning how not to bump into things. Nearby, a robot with a skull for a head works on combining the input from his various senses — audio, video, ultrasonics, radar and infrared — to interpret what's going on around it.
In another lab on campus, computers are being controlled by living tissue taken from the brains of rats.
But Warwick's most daring experiments have been on himself. On Aug. 24, 1998, as the British Broadcasting Corp. filmed, doctors made a small incision in Warwick's left arm, slid in a thin inchlong glass capsule, and stitched him up.
The capsule contained silicon microchips that announced Warwick's presence to computers. His office doors swung open as he approached. Lights flicked on as he entered. His computer said hello and told him how many e-mails were waiting.
That chip stayed in for a couple of weeks. It's now on display at the Science Museum in London.
In 2002, doctors sliced open Warwick's left wrist and implanted a much smaller and more sophisticated device. For three months, its 100 electrodes were connected to his median nerves, linking his nervous system to a computer.
"I moved my hand, and my neural signals were sent over the Internet to open and close a robot hand," he said.
Not only that: The robotic hand had sensors. As it grasped a sponge or a glasses case, it sent information back to Warwick.
"It was tremendously exciting," Warwick said. "I experienced it as signals in my brain, which my brain was quite happy to recognize as feedback from the robot hand fingertips."
The research has significant medical implications.
Paralyzed people might regain some movement if one chip was implanted above the break in the nerves and another was implanted below to receive the impulses, Warwick said.
More intelligent chips in the brains of people with Parkinson's disease might sense when tremors were on the way and signal the brain to stop them.
"It's like a computer brain out-thinking a human brain," he said.
Warwick's biggest experiment, in which he will have a chip implanted in his brain, is seven or eight years away. He will attempt thought communication — "literally the first brain-to-brain communication," he said.
"That excites me beyond all proportion," he said. "Nothing is going to stop me from doing that."
Not everyone approves of Warwick's research. From time to time, he receives missives from people he calls religious extremists, telling him he is tampering with God's work.
And in an opinion piece this month in the Toronto Star, Kevin Haggerty, an associate professor of criminology at the University of Alberta, called Warwick part of the "advance guard" trying to expand chip technology as much as possible. The day will come, Haggerty warned, when all people will be implanted with computer chips and government will be able to track them all the time, recording their smallest behavioral traits.
Warwick acknowledges that the technology raises ethical questions. In the hands of a malign government, he said, it could be used to horrendous effect. But it can be used to good effect as well, he said.
"Ethically, the technology is there," he said. "I show people what it can do."
Despite differing over the desirability of implantation, Warwick and Haggerty agree on a great deal.
For one thing, the procedure, unheard of until recently, is becoming more common.
More pet owners are taking advantage of chip implants in dogs and cats that transmit identification to veterinarians and animal shelters.
Patrons of the Baja Beach Clubs in Barcelona, Spain, and Rotterdam, Netherlands, can have a microchip injected into their arms to get access to VIP lounges and pay for drinks without waiting in line.
For another, one early use of chips to track humans might involve sex offenders. Haggerty views this as a way to get the public used to human tracking. Warwick can envision officers trying to solve a crime pressing a button and seeing instantly the locations of all known sex offenders in a certain area.
And both men foresee a time when most people will be implanted with chips. For Warwick, that is because the advantages will be so obvious — increased memory, better ability to analyze and compare, the ability to think in more dimensions, the possibility of sensing the world in different ways.
But there will be, he said, important questions to answer.
"Is it OK to upgrade? What about the people who don't upgrade?" he asked. "If they don't upgrade, they could become some sort of subspecies."

Wednesday, February 21, 2007

2/21/07: Meeting Minutes

Preview Weekend:
Misti Marr is organizing a 5-15 minute presentation to be given to BME grad student applicants interested in Neuroengineering during their lunch hour on Friday (12:30 – 1:30 pm).

The presentation will discuss life as a grad student, and will cover:
(1) research (short descriptions, similar to what is listed on the website)
(2) NETI, briefly
(3) classes people took or are taking, especially those that are unique to Hopkins
(4) extracurricular activities (a.k.a. the “look we actually have a life outside of school” section)

Send pictures to Misti Marr by next week Monday (2/26/07) to be included in the presentation. There will be a meeting with Reza Shadmehr next week (most likely Thursday) after the presentation has been compiled.

Scholarship Essay Contest
Nasir Bhanpuri presented preliminary ideas regarding the essay contest. A competition targeted at high school students to promote interest in Neuroengineering was agreed upon, with a small ($100-$500) prize offered as a reward. Potentially there will be two categories for entries, one more ethical and one more technical, with a first prize (monetary) and honorable mention awarded in each.

The finalized version will be solicited to guidance counselors of local Baltimore high schools, with an online form through which entries can be submitted. Judging may be done at a meeting with everyone present and having a couple people rate each essay so the ratings are more fair.

A more finalized version will be presented at the next meeting.

EMBS Neural Engineering Conference, Kohala, HI
Plans are being made to attend the EMBS conference May 2-5, currently being organized by Natan Davidovics and Gabriel Colon. Those interested in attending also include Nasir Bhanpuri, Chris Smith, and Aaron Wong. Those planning to stay longer must pay for the extra days out of pocket.

Next Meeting
The date and for the next meeting was not finalized, but it was agreed that meeting locations should alternate between the Med campus and Homewood. Keep an eye out for an email regarding the next meeting.

Tuesday, February 20, 2007

NEWRON vol I issue II (2-16-07)

Edited by: Natan Davidovics


Chipping In
Scientific American (02/07) Vol. 296, No. 2, P. 18; Griffith, Anna

http://web.ebscohost.com/ehost/detail?vid=6&hid=5&sid=5b2cd464-20bd-405f-8ff1-6808e53373f7%40sessionmgr9
(Full article is included below if the link gives you trouble)

Scientists are working on a "brain chip" designed as a memory aid, especially in cases where the patient has suffered neural damage. A team from the University of Southern California is getting ready for live tests of a neural prosthesis in brain-damaged rats, which may be carried out in the spring. In January 2006 USC researcher Theodore W. Berger and his team engineered a silicon chip that imitates biological neurons in tissue slices of rat hippocampus as a replacement for a section of brain that was surgically removed, and that returns function by processing neural input into appropriate output with a 90 percent rate of accuracy.



The Mind Chip
New Scientist (02/03/07) Vol. 193, No. 2589, P. 28; Fox, Douglas

Click Here to View Full Article (may not work so I included an extended summary)

A notable achievement in computer vision has been made by researcher Kwabena Boahen and colleagues at the University of Pennsylvania in Philadelphia, who constructed a device that can see via chips that physically imitate the electrical activity of neurons in the primary visual cortex. "I want to figure out how the brain works in a very nuts-and-bolts way," explains Boahen. "I want to figure it out such that I can build it." Boahen aims to top his accomplishment of building an artificial retina with the creation of an artificial cerebral cortex through the generalization of the chip's function; such a breakthrough may be an important step in helping restore neural function to people impaired by disease or injury. The concept of the artificial neuron as a technology for enabling brain-like computing in real time was first suggested in the late 1980s by California Institute of Technology scientist Carver Mead, who discovered he could build such circuits by having digital processors use transistors in their analog amplifier phase instead of their on/off switching phase. Mounted on the surface of Boahen's artificial retina are photosensitive transistors that translate incoming light into analog voltages with a value determined by the light's intensity and which last for as long as the light is beamed onto the transistors; these transmissions are routed to the artificial retina neurons where motion and regions of contrast are recognized, signaling the edges of objects in the image. Processing information about edges and movement in the visual scene is carried out by the low-power visual cortex chips, which build object outlines out of the signals. A successful cortical implant will have to be able to mimic the plasticity of the brain's neural network, in which connections between neurons are created and adapted on the fly.



Loving with all your ... brain

Cnn.com, Elizabeth Cohen

Loving with all your ... brain - CNN.com*

hese areas of the brain, while little known to most people, are helping scientists explain the physiological reasons behind why we feel what we feel when we fall in love. By studying MRI brain scans of people newly in love, scientists are learning a lot about the science of love: Why love is so powerful, and why being rejected is so horribly painful.


BRAIN CHIP FOR MEMORY REPAIR CLOSES IN ON LIVE TESTS

Supplementing the human brain with computer power has been a staple of science fiction. But in fact, researchers have taken several steps in melding minds with machines, and this spring a team from the University of Southern California may replace damaged brain tissue in rats with a neural prosthesis.

For the past few years, researchers have demonstrated the ability to translate another creature's thoughts into action. In 2000 neurologist Miguel Nicolelis of Duke University wired a monkey with electrodes so that its thoughts could control a robotic arm. Brain-machine interfaces developed by Niels Birbaumer, a neuroscientist at the University of Tübingen in Germany, already help some paralyzed patients move a computer cursor with their brain waves to select letters for writing a message.

Theodore W. Berger and his U.S.C. colleagues have developed the first brain-machine interface to communicate back to the brain. Last January they used a silicon chip to mimic biological neurons in tissue slices of rat hippocampus, the hub for memory sorting and storage. The chip replaced a surgically removed section of the hippocampus and restored function by processing incoming neural signals into appropriate output with 90 percent accuracy.

The biomedical engineers had been on the verge of testing a chip in hippocampal slices for several years, but roadblocks slowed work. Existing electrode array technology would not function well in tissue slices, forcing the researchers to construct their own. Cutting the hippocampus slices just right to keep the neural pathway intact was also difficult.

Because building the one-millimeter-square chip costs tens of thousands of dollars and takes several months, the planned spring test will actually rely on a model of that chip --specifically a larger, reprogrammable device linked to a computer called a field programmable gate array (FPGA). The FPGA will allow investigators to easily test and modify their new mathematical model of neural communication for living rats before committing it to a chip. Sam Deadwyler, a professor of physiology and pharmacology at Wake Forest University and a collaborator in the study, has demonstrated that stimulating the hippocampus of living rats with a certain pattern of activity can increase performance on a memory task, such as recalling which lever will dispense water. In a few months he will use the FPGA mathematical model to predict hippocampal activity. If the model is correct, the artificial implant should restore memory for such tasks in rats with drug-induced amnesia.

For more complicated animal models, U.S.C. physicist Armand Tanguay suggests a multichip module to facilitate the transition. Light beams would transmit signals between neuron units on multiple chip layers. Unlike wires, light beams pass directly through one another without interference, allowing for many more interconnections. The result: a web of light between silicon chips mimicking a dense neural network.

"Many challenges will be encountered as the researchers move from in vitro to in vivo studies in the rat," says Grace Peng, a program director at the National Institutes of Health's Division of Discovery Science and Technology. In fact, the team is not quite sure what to expect once it goes to live animals. Avoiding rejection by the immune system might mean anchoring cell adhesion molecules to the chip so that the surface of the implant looks like tissue, says U.S.C. chemist Mark Thompson. Neural plasticity, or the brain's ability to reorganize its connections, could also pose a problem by preventing the formation of stable connections between the neurons and chip. "In other application areas such as motor control or perception, plasticity and adaptability of the brain usually facilitate the effects of artificial interfaces," Peng notes optimistically.

One other possible concern, if such implants make it to human testing: Might bypassing damaged neurons in the hippocampus also bypass connections with other areas of the brain that filter what we remember? In other words, would the brain become unable to purge memories? If so, that would make the implant a truly unforgettable device.

DIAGRAM: HEADSTRONG: Implants communicating with the hippocampus might someday restore or improve memory, if such devices succeed in rat tests.

~~~~~~~~

By Anna Griffith

Anna Griffith is based in Chico, Calif.



Sunday, February 11, 2007

NEWRON vol I issue I (2-9-07)

Edited by: Natan Davidovics


http://www.newswise.com/p/articles/view/527140/

Mimicking How the Brain Recognizes Street Scenes

Scientists in Tomaso Poggio's laboratory at the McGovern Institute for Brain Research at MIT developed a computational model of how the brain processes visual information and applied it to a complex, real world task: recognizing the objects in a busy street scene. The researchers were pleasantly surprised at the power of this first application of a biologically inspired computer model for artificial vision, which has many potential practical applications.

http://www.wired.com/news/technology/medtech/1,72580-0.html

A Wheelchair That Reads Your Mind


Patients who suffer from disease or injury that leave them unable to move have little hope of independent mobility. But that may be about to change. Researchers are developing a thought-controlled robotic wheelchair.


http://www.newscientisttech.com/channel/tech/dn10963-brain-activity-provides-novel-biometric-key.html

Brain activity provides novel biometric key

An electronic security system that identifies people by monitoring the unique pattern of electrical activity within their brain is being tested by European scientists.

Wednesday, February 07, 2007

2/7/07: Meeting Minutes

Meeting Minutes: NeuroEngineering Training Initiative: 2/7/07

Stuff we need to do:
-Submit conferences, workshops to Andrew
-If you email anything, or if you've got information, send it to neuroengineering@gmail.com

neuroengineering@gmail.com = archive
neuroengineering@googlegroups.com = mailing list

Officer Elections
President: Issel Lim
  • Organizes meetings, emails people, coordinates w/ Dr. Thakor
  • Takes care of mailing lists
    Vice President: Misti Marr
  • Organizes summer seminar
    Secretary: Aaron Wong
  • Meeting minutes
  • Publicity/Newsletter?
  • Compiling the progress reports
  • Takes care of the blog: Aaron, Nasir, Luke
    Treasurer/Fundraiser: Gabriel Colon
  • Possible Fundraiser for April/Spring: Activities Fair/Spring Festival
  • Reimbursement
  • JHU account or credit card (ask Allen Strong)
  • Keeps track of budget
  • We usually spend money on food, cups, plates, beer, dinner.
    Webmaster: Andrew Cassidy (website)
  • Webpage
  • Write a "how-to" manual for how to edit the website
  • Compile/Post list of fellowships, etc.

    Committees/Tasks:
    Curriculum: Chris Smith, Luke Johnson, Natan Davidovics
  • Compiles lists of classes, who's taking/taken them
  • Which classes to take for each focus
  • Which professors did you have on your GBO? (w/ sample questions, so we know whom to put on our mock GBOs)
  • (Debbie/Issel : send Chris the information)

    Symposium/Events: Gabriel Colon
  • Invite big speakers for a day (spend neuroeng money)
  • Or travel to some other university for that
  • Ski trip, camping, etc, for networking purposes
  • Paintball, laser tag,
  • ... Email Gabriel your ideas.

    Summer Seminar: Luke Johnson, Nasir Bhanpuri
  • Students talk about their research, past rotations

    Newsletter/Current Events/"In the News": Natan Davidovics
  • What's going on in the news
  • Email him w/ links

    Interview Weekend: Misti Marr
  • Neuroengineering lunch
  • Meet on Feb 21st: Wednesday @ 130p Clark 311 @ Feb 21st

    Entrepreneurialship: Debbie Castillo, Aaron Wong
  • Business opportunities; meeting w/ industries;
  • Job opportunities for neuroengineers
  • Speakers; alumni from NETgrant

    High School / Undergrads: Nasir Bhanpuri, Aaron Wong
  • Get younger students thinking about neuroengineering
  • College scholarships ($1000)
  • Submit essay and resume
  • Give information to guidance counselors at high schools
  • Connect w/ Dunbar Incentives Mentoring Program (Sarah Hemminger)

    Summer Tasks
    Clinical neuroengineering class/summer project
  • Solve faculty problems, write a proposal
  • Recommend as a BME senior design project
  • Trainees could be TAs for that class
  • Get clinicians to email us their problems; compile a list, organize design project

    Fall Seminar
  • Introduce professors (chalk talks) in September so first years can choose rotations

    Big Sibs/Little Sibs
  • Answers first-year questions. (Refer to past blog entries for details.)


    How often to have meetings:
    Spring 2007: Wednesdays at 130p in Clark 311
    Next meeting: Wednesday @ 130p Clark 311 @ Feb 21st; Neuroengineering

    Preview Weekend:
  • Tour of Homewood Campus
  • Tour of Hospital + Meet at Med Campus
  • March 2nd: Gabriel Colon
  • March 9th: Issel Lim
    Meet students from Homewood and bring them to Talbot Library; Dr. Thakor will give a talk at 1100p.
    Ask other alumni if they want to help w/ presentation
    Presentation @ 100p: Debbie, Misti, Aaron, Chris, Gabriel, Natan, Issel
    (neuroengineering grad students @ Hopkins)

    Stipend increasing! :)

    Email / Information:
    Please email Andrew Cassidy any conferences, workshops, and/or fellowships that would be suitable for neuroengineers.

    When you send out emails or documents, please also send a copy to "neuroengineering@gmail.com" so that we'll have a searchable archive of information.

    neuroengineering@googlegroups.com is the mailing list for all of the people currently on the grant.
    neuroengineering2@googlegroups.com is for Hopkins students interested in NETI, our events, our seminars, etc.

    http://neuroengineering.bme.jhu.edu
    is the current website, and it's currently being managed by Andrew Cassidy.
    http://neuroengineering.blogspot.com
    is the blog, on which we can put more "internal affairs" sort of things -- for example, the links/news that Natan sends out, the meeting minutes, etc.

    The minutes have been emailed. Thanks for coming to the meeting! The next one will be on February 21st in Clark 311 at 130p.

    Email from Dr. Reza Shadmehr:
    Dear colleagues:

    The BME grad student applicants are visiting on March 2 and 9th. This is my
    current rough draft of their schedule.

    The neuro students will start their day at Homewood at 8AM with a talk by
    Rai Winslow. They will then get a tour of Mind/Brain, starting at around
    9AM. I wonder if Lauren and Sia could take the students from Clark Hall to
    Mind/Brain and along the way give them a brief tour of the campus. The
    Mind/Brain tour should end by around 10:30, at which point the students will
    be put on a bus and brought to medschool. It would be great if some of the
    current neuroengineering students including Issel, Natan, and Gabriel could
    meet the students upon arrival and bring them to Talbot library. At around
    11:00, I will give a 15 minute intro to the various labs at medschool and
    lay out the schedule for the rest of the day. I will then take the students
    to the FMRI center for a tour by Jim Pekar.

    Around 12:30, we will return to Talbot to have lunch. During the hour long
    period, Nitish will give a description of the neuroengineering program. I
    think it would also be great if the students put on a presentation, talking
    about life as a grad student at Hopkins.

    Around 1:30 we will leave for a tour of the hospital, focusing on the
    epilepsy monitoring unit and a discussion led by Greg Bergey. From
    2:30-4:30 the students have free time to visit the various labs and talk to
    professors of their choice. A student panel starts at 4:30.

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